Chih-Hsin Tang Selected Research

Chemokine CCL5

6/2016	CCL5 promotes VEGF-C production and induces lymphangiogenesis by suppressing miR-507 in human chondrosarcoma cells.
2/2015	CCL5 promotes vascular endothelial growth factor expression and induces angiogenesis by down-regulating miR-199a in human chondrosarcoma cells.
1/2015	CCL5/CCR5 axis induces vascular endothelial growth factor-mediated tumor angiogenesis in human osteosarcoma microenvironment.
11/2014	CCL5 promotes VEGF-dependent angiogenesis by down-regulating miR-200b through PI3K/Akt signaling pathway in human chondrosarcoma cells.
1/2012	CCL5 and CCR5 interaction promotes cell motility in human osteosarcoma.
1/2010	Involvement of matrix metalloproteinase-3 in CCL5/CCR5 pathway of chondrosarcomas metastasis.
8/2009	CCL5/CCR5 axis promotes the motility of human oral cancer cells.
3/2009	CCL5 increases lung cancer migration via PI3K, Akt and NF-kappaB pathways.

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Chih-Hsin Tang Research Topics

Disease

152	Neoplasms (Cancer) 02/2022 - 04/2005
93	Neoplasm Metastasis (Metastasis) 01/2022 - 04/2005
82	Chondrosarcoma 11/2021 - 03/2008
37	Osteoarthritis 06/2022 - 09/2007
37	Rheumatoid Arthritis 01/2022 - 09/2007
32	Inflammation (Inflammations) 01/2022 - 03/2010
28	Osteosarcoma (Osteogenic Sarcoma) 11/2021 - 01/2004
23	Prostatic Neoplasms (Prostate Cancer) 04/2022 - 09/2008
16	Mouth Neoplasms (Oral Cancer) 01/2022 - 08/2008
15	Lung Neoplasms (Lung Cancer) 02/2019 - 12/2007
14	Breast Neoplasms (Breast Cancer) 01/2022 - 04/2005
14	Arthritis (Polyarthritis) 10/2020 - 09/2007
13	Experimental Arthritis 01/2022 - 07/2015
11	Carcinogenesis 01/2021 - 04/2009
11	Hypoxia (Hypoxemia) 01/2020 - 10/2006
11	Obesity 01/2020 - 11/2005
10	Lymphatic Metastasis 01/2022 - 01/2013
10	Squamous Cell Carcinoma of Head and Neck 01/2022 - 07/2011
8	Osteoporosis 11/2021 - 10/2007
7	Wilms Tumor (Wilm's Tumor) 01/2022 - 03/2011
7	Infections 01/2022 - 10/2011
6	Bone Resorption 01/2021 - 06/2008
6	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 05/2010
5	Triple Negative Breast Neoplasms 03/2021 - 11/2015
4	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2020
4	Disease Progression 10/2020 - 01/2013
4	Carcinoma (Carcinomatosis) 01/2019 - 04/2005

Drug/Important Bio-Agent (IBA)

47	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2004
39	IntegrinsIBA 04/2022 - 01/2004
35	CytokinesIBA 01/2022 - 06/2008
28	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 02/2013
23	NF-kappa B (NF-kB)IBA 09/2010 - 12/2007
21	Matrix Metalloproteinases (MMPs)IBA 07/2021 - 09/2007
20	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2020 - 02/2009
19	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 08/2021 - 09/2007
19	Small Interfering RNA (siRNA)IBA 01/2021 - 12/2007
18	ResistinIBA 08/2021 - 01/2015
17	LigandsIBA 11/2021 - 10/2007
15	Interleukin-6 (Interleukin 6)IBA 01/2021 - 10/2007
13	AdipokinesIBA 01/2022 - 12/2014
13	Messenger RNA (mRNA)IBA 11/2021 - 01/2008
13	Conditioned Culture MediaIBA 09/2021 - 01/2008
13	ChemokinesIBA 07/2018 - 09/2007
12	CC ChemokinesIBA 11/2021 - 03/2009
11	MelatoninIBA 04/2022 - 01/2019
11	Biological ProductsIBA 01/2022 - 01/2014
11	AdiponectinIBA 10/2021 - 10/2007
11	Vascular Endothelial Growth Factor CIBA 09/2021 - 01/2016
11	Monoclonal AntibodiesIBA 01/2012 - 04/2005
11	Integrin alphaVbeta3IBA 10/2009 - 04/2005
10	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 09/2020 - 09/2010
9	LeptinIBA 08/2021 - 08/2008
9	Biomarkers (Surrogate Marker)IBA 01/2021 - 07/2011
8	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 06/2022 - 05/2013
8	Chemokine CCL5IBA 06/2016 - 03/2009
7	Peptides (Polypeptides)IBA 02/2022 - 02/2009
7	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 01/2022 - 10/2014
7	erucylphosphocholineIBA 01/2021 - 01/2016
7	AmphiregulinIBA 01/2020 - 05/2015
7	Antineoplastic Agents (Antineoplastics)IBA 01/2020 - 04/2012
7	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 01/2012 - 02/2009
6	ErbB Receptors (EGF Receptor)IBA 01/2022 - 11/2015
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 11/2012
6	Matrix Metalloproteinase 2 (Gelatinase A)IBA 08/2021 - 01/2013
6	Phenobarbital (Luminal)FDA Link 03/2021 - 01/2016
6	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 07/2018 - 06/2008
6	Connective Tissue Growth FactorIBA 10/2017 - 05/2009
6	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 11/2015 - 10/2006
6	Protein Isoforms (Isoforms)IBA 01/2014 - 10/2007
6	MAP Kinase Kinase Kinase 5IBA 07/2013 - 11/2008
5	Nicotinamide PhosphoribosyltransferaseIBA 01/2022 - 03/2019
5	EnzymesIBA 12/2021 - 03/2010
5	MicroRNAs (MicroRNA)IBA 10/2021 - 06/2014
5	Pharmaceutical PreparationsIBA 03/2021 - 07/2011
5	Interleukin-8 (Interleukin 8)IBA 01/2021 - 06/2008
5	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 02/2011
5	HMGB1 Protein (HMG1)IBA 10/2020 - 01/2016
5	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2020 - 01/2012
5	OsteopontinIBA 02/2017 - 06/2009
5	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 06/2013 - 02/2010
5	U 0126 (UO 126)IBA 01/2012 - 02/2009
5	Chemokine CXCL12IBA 10/2009 - 09/2007
4	Tyrosine Kinase InhibitorsIBA 01/2022 - 11/2015
4	Progesterone Receptors (Progesterone Receptor)IBA 01/2022 - 11/2019
4	Transcription Factors (Transcription Factor)IBA 08/2021 - 09/2007
4	human ERBB2 proteinIBA 03/2021 - 01/2016
4	Cysteine (L-Cysteine)FDA Link 03/2021 - 10/2017
4	Endothelin-1 (Endothelin 1)IBA 01/2021 - 08/2012
4	Hormones (Hormone)IBA 01/2021 - 01/2016
4	ApelinIBA 01/2021 - 03/2019
4	Angiopoietin-2IBA 01/2020 - 10/2017
4	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2020 - 07/2015
4	Caspase 3 (Caspase-3)IBA 12/2018 - 10/2013
4	Matrix Metalloproteinase 13IBA 01/2018 - 02/2009
4	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2017 - 01/2013
4	ResveratrolIBA 01/2017 - 02/2015
4	Cytochromes c (Cytochrome c)IBA 12/2016 - 04/2012

Therapy/Procedure

24	Therapeutics 04/2022 - 04/2005
17	Drug Therapy (Chemotherapy) 08/2021 - 05/2010
15	Radiotherapy 01/2020 - 05/2010